Publication List Dr. Thomas Nauser

Publications 1993-2023

88. T. de Wild, T. Nemeth, P. Becker, D. Günther, T. Nauser, T. J. Schmidt, and L. Gubler. Repair of aromatic hydrocarbon-based membranes tested under accelerated fuel cell conditions. Journal of Power Sources 560:232525, 2023. (https://doi.org/10.1016/j.jpowsour.2022.232525)

87. S. Patra, I. Mosiagin, R. Giri, T. Nauser, and D. Katayev. Electron-Driven Nitration of Unsaturated Hydrocarbons. Angew.Chem.Int.Ed. 62 (28):e202300533, 2023. (https://doi.org/10.1002/anie.202300533)

86. T. de Wild, J. Wurm, P. Becker, D. Günther, T. Nauser, T. J. Schmidt, L. Gubler, and T. Nemeth. A Nature-Inspired Antioxidant Strategy based on Porphyrin for Aromatic Hydrocarbon Containing Fuel Cell Membranes. ChemSusChem e202300775, 2023. (https://doi.org/10.1002/cssc.202300775)

85. L. Gubler, T. de Wild, T. Nemeth, and T. Nauser. Radical Attack and Damage Mitigation in Hydrocarbon-Based Ionomers. ECS Transactions 112 (4):305-313, 2023. (https://doi.org/10.1149/11204.0305ecst)

84. T. Nemeth, T. Nauser, and L. Gubler. On the Radical Induced Degradation of Quaternary Ammonium Cations for Anion-Exchange Membrane Fuel Cells and Electrolyzers. ChemSusChem 15 (22):e202201571, 2022 (https://doi.org/10.1002/cssc.202201571)

83. T. Nemeth, T. de Wild, L. Gubler, and T. Nauser. Moderation of Oxidative Damage on Aromatic Hydrocarbon-Based Polymers. J.Electrochem.Soc. 169:054529, 2022. (https://doi.org/10.1149/1945-7111/ac6f85)

82. T. Nemeth, M. Agrachev, G. Jeschke, L. Gubler, and T. Nauser. EPR Study on the Oxidative Degradation of Phenyl Sulfonates, Constituents of Aromatic Hydrocarbon-Based Proton-Exchange Fuel Cell Membranes. J.Phys.Chem.C, 2022. (https://doi.org/10.1021/acs.jpcc.2c04566)

81. Nemeth, T.; de Wild, T.; Gubler, L.; Nauser, T. Impact of substitution on reactions and stability of one-electron oxidised phenyl sulfonates in aqueous solution, Phys. Chem. Chem. Phys., 2022, 24(2), 895. https://pubs.rsc.org/en/content/articlepdf/2022/cp/d1cp04518k (DOI: 10.1039/d1cp04518k)

80. Gebicki, J.M.; Nauser, T. Initiation and Prevention of Biological Damage by Radiation-Generated Protein Radicals. Int. J. Mol. Sci. 2022, 23, 396. https://www.mdpi.com/1422-0067/23/1/396 (DOI: 10.3390/ijms23010396)

79. Nemeth, T.; de Wild, T.; Gubler, L.; Nauser, T. The application of Pulse Radiolysis to elucidate the degradation mechanism of aromatic hydrocarbon-based proton exchange fuel cell membranes, EPA Newsletter, 2021, 101, 15, Europan Photochemical Association. https://www.photochemistry.eu/wp-content/uploads/2022/01/December_2021_EPA-Newsletter.pdf)

78. J. M. Gebicki and T. Nauser. Fast Antioxidant Reaction of Polyphenols and Their Metabolites. Antioxidants 10 (8):1297, 2021.(https://doi.org/10.3390/antiox10081297)

77. K. Liosi, A. J. Stasyuk, F. Masero, A. A. Voityuk, T. Nauser, V. Mougel, M. Solá, and Y. Yamakoshi. Unexpected Disparity in Photoinduced Reactions of C60 and C70 in Water with the Generation of O2·- or 1O2. JACS Au, 2021. (https://doi.org/10.1021/jacsau.1c00239)

76. T. de Wild, T. Nemeth, T. M. Nolte, T. J. Schmidt, T. Nauser, and L. Gubler. Possible Repair Mechanism for Hydrocarbon-Based Ionomers Following Damage by Radical Attack. J.Electrochem.Soc 168 (5):054514, 2021. (http://dx.doi.org/10.1149/1945-7111/abf9be)  

75. T. M. Nolte, T. Nauser, L. Gubler, A. J. Hendriks, and W. J. G. M. Peijnenburg. Thermochemical unification of molecular descriptors to predict radical hydrogen abstraction with low computational cost. Physical Chemistry Chemical Physics 22 (40):23215-23225, 2020. (http://dx.doi.org/10.1039/D0CP03750H)

74. T. Nauser and J. M. Gebicki. Addition of carbon-centered radicals to aromatic antioxidants: mechanistic aspects. Physical Chemistry Chemical Physics 22 (42):24572-24582, 2020. (http://dx.doi.org/10.1039/D0CP04469E)

73. R. Calvo, A. Le Tellier, T. Nauser, D. Rombach, D. Nater, and D. Katayev. Synthesis, Characterization and Diverse Reactivity of a Hypervalent Iodine-Based Nitrooxylating Reagent. Angew.Chem.Int.Ed. 59 (39):17162-17168, 2020. (https://doi.org/10.1002/anie.202005720)

72. T. M. Nolte, T. Nauser, and L. Gubler. Attack of hydroxyl radicals to a-methyl-styrenesulfonate polymers and cerium-mediated repair via radical cations. Phys.Chem.Chem.Phys. 22:4516-4525, 2020.

71. W. H. Koppenol, S. Serrano-Luginbuehl, T. Nauser, and R. Kissner. Thinking Outside the Cage: A New Hypothesis That Accounts for Variable Yields of Radicals from the Reaction of CO2 with ONOO-. Chem.Res.Toxicol. 33 (7):1516-1527, 2020.

70. T. Nauser and J. M. Gebicki. Fast reaction of carbon free radicals with flavonoids and other aromatic compounds. Arch.Biochem.Biophys. 674:108107, 2019.

69. T. Nauser and J. M. Gebicki. Antioxidants and Radical Damage in a Hydrophilic Environment - Chemical Reactions and Concepts. Essays Biochem, 2019.

68. N. Santschi, B. J. Jelier, S. Stähelin, and T. Nauser. Profiling the oxidative activation of DMSO-F6 by pulse radiolysis and translational potential for radical C-H trifluoromethylation. Organic & Biomolecular Chemistry 17 (45):9734-9742, 2019.

67. L. Gubler, T. Nolte, and T. Nauser. Antioxidant Strategies for Hydrocarbon-Based Membranes. ECS Transactions 86 (13):369-379, 2018.

66. L. Gubler, T. Nauser, F. D. Coms, Y. H. Lai, and C. S. Gittleman. Prospects for Durable Hydrocarbon-Based Fuel Cell Membranes. Journal of the Electrochemical Siciety 165 (6):F3100-F3103, 2018.

65. H Erdogan, A. Vandemeulebroucke, T. Nauser, P. L. Bounds, and W. H. Koppenol. Jumpstarting the Cytochrome P450 Catalytic Cycle with a Hydrated Electron. Journal of Biological Chemistry 291 (52):21841-21849, 2017.

64. T. Nauser and J. M. Gebicki. Reaction rates of glutathione and ascorbate with alkyl radicals are too slow for protection against protein peroxidation in vivo. Arch.Biochem.Biophys, 633:118-123, 2017.  

63. N. Santschi, and T. Nauser, An experimental electrophilicity index. Chem.Phys.Chem., 18(21): 2973-2976, 2017.

62. T. Nauser and J. M. Gebicki. Physiological concentrations of ascorbate cannot prevent the potentially damaging reactions of protein radicals in humans. Chem.Res.Toxicol. 30:1702-1710, 2017.

61. N. Santschi, B. Jelier, and T. Nauser. Mechanistic Insight into the Thermal Activation of Togni's Trifluoromethylating Reagents. Phys.Chem.Chem.Phys. 19:18172-18177, 2017.

60. N. Santschi, and T. Nauser. Rate of single electron reduction of Togni's reagent. J.Fluorine.Chem, 218-222, 2017.

59. S. Yakunin, D. N. Dirin, Y. Shynkarenko, V. Morad, I. Cherniukh, O. Nazarenko, D. Kreil, T. Nauser, and M. V. Kovalenko. Detection of gamma photons using solution-grown single crystals of hybrid lead halide perovskites. Nature Photonics, 2016.

58. C. Gstrein, P. Walde, A. D. Schlüter, and T. Nauser. Shielding effects in spacious macromolecules: a case study with dendronized polymers. Photochem.Photobiol.Sci. 15:964-968, 2016.

57. L. Mahmoudi, R. Kissner, T. Nauser, and W. H. Koppenol. Electrode Potentials of of L-Tryptophan, L-Tyrosine, 3-Nitro-L-tyrosine, 2,3-Difluoro-L-tyrosine, and 2,3,5-Trifluoro-L-tyrosine. Biochemistry 55(20):2849-2856, 2016.

56. J. Thoegersen, R. Kissner, T. Nauser, W.H. Koppenol, B. Richter, F. Jensen, S. R. Keiding, and S. J. K. Jensen. Primary photochemistry of peroxynitrite in aqueous solution: Chem. Phys. Lett. 641:187-192, 2015.

55. T. Nauser, W. H. Koppenol, and C. Schöneich. Protein thiyl radical reactions and product formation: a kinetic simulation. Free Radical Biol.Med.80:158-163, 2015.

54. T. Nauser, D. Steinmann, G. Grassi, and W. H. Koppenol. Why Selenocysteine Replaces Cysteine in Thioredoxin Reductase: A Radical Hypothesis. Biochemistry 53 (30):5017-5022, 2014.

53. T. Nauser and A. Carreras. Carbon-centered radicals add reversibly to histidine - implications. Chem.Comm. 50 (92):14349-14351, 2014.

52. A. B. Das, T. Nauser, W. H. Koppenol, A. J. Kettle, C. C. Winterbourn, and P. Nagy. Rapid reaction of superoxide with insulin-tyrosyl radicals to generate a hydroperoxide with subsequent glutathione addition. Free Radical Biol.Med. 70:86-95, 2014.

51. C. Schöneich, O. Mozziconacci, W. H. Koppenol, and T. Nauser. Intramolecular 1,2- and 1,3-Hydrogen Transfer Reactions of Thiyl Radicals. Isr.J.Chem 54:265-271, 2014.

50. A. Domazou, J. M. Gebicki, T. Nauser, and W. H. Koppenol. Repair of Protein Radicals by Antioxidants. Isr.J.Chem 54:254-264, 2014.

49. A. Grotzky, E. Altamura, J. Adamcik, P. Carrara, P. Stano, F. Mavelli, T. Nauser, R. Mezzenga, A. D. Schluter, and P. Walde. Structure and Enzymatic Properties of Molecular Dendronized Polymer-Enzyme Conjugates and Their Entrapment inside Giant Vesicles. Langmuir 29 (34):10831-10840, 2013.

48. M. Dragic, F. Maier, C. Hultsch, P. Weinig, T. Nauser, C. Smuda, and D. Loeffler. Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof. Anonymous. Anonymous. Piramal Imaging SA, Germany . (WO2013093099A1):70pp, 2013.

47. D. Hofstetter, B. Thalmann, T. Nauser, and W. H. Koppenol. Hydrogen Exchange Equilibria in Thiols. Chem.Res.Toxicol. 25:1862-1867, 2012.

46. A. Grotzky, T. Nauser, H Erdogan, A. D. Schlüter, and P Walde. A Fluorescently Labeled Dendronized Polymer.Enzyme Conjugate Carrying Multiple Copies of Two Different Types of Active Enzymes. J.Am.Chem.Soc. 134:11392-11395, 2012.

45. M. R. Filipovic, J. L. Miljkovic, T. Nauser, M. Royzen, K. Klos, T. Shubina, W. H. Koppenol, S. J. Lippard, and I. Ivanovic-Burmazovic. Chemical Characterization of the Smallest S-Nitrosothiol, HSNO; Cellular Cross-talk of H2S and S-Nitrosothiols. J.Am.Chem.Soc. 134:12016-12027, 2012.

44. W. H. Koppenol, P. L. Bounds, T. Nauser, and R. Kissner. Peroxynitrous acid: controversy and consensus surrounding an enigmatic oxidant.  Dalton Trans. 41:13779-13787, 2012.

43. T. Nauser, C. Schöneich, W.H. Koppenol. Reversible Hydrogen Transfer Reactions in Thiyl Radicals From Cysteine and Related Molecules: Absolute Kinetics and Equilibrium Constants Determined by Pulse Radiolysis. J.Phys.Chem. B 116(18): 5329-5341. 2012.

42. T. Nauser, D.Steinmann, W.H. Koppenol. Why do proteins use selenocysteine instead of cysteine? Amino Acids  42(1), 39-44. 2012.

41. S.F. Wnuk, J.A. Penjarla, T. Dang, A.M.  Mebel, T. Nauser, C. Schoneich. Modeling of the ribonucleotide reductases substrate reaction. Hydrogen atom abstraction by a thiyl free radical and detection of the ribosyl-based carbon radical by pulse radiolysis. Collection of Czechoslovak Chemical Communications 76(10), 1223-1238. 2011.

40. M. Trummer, T. Nauser, M.-L. Lechner, F. Uhlig, and W. Caseri. Stability of polystannanes towards light. Polymer Degradation and Stability 96:1841-1846, 2011.

39. R. S. Glass, C. Schöneich, G. S. Wilson, T. Nauser, T. Yamamoto, E. Lorance, G. S. Nichol, and M. Ammam. Neighboring Pyrrolidine Amide Participation in Thioether Oxidation. Methionine as a "Hopping" Site. Org.Lett. 13 (11):2837-2839, 2011.

38. H. Botti, M. N. Moller, D. Steinmann, T. Nauser, W. H. Koppenol, A. Denicola, and R. Radi. Distance-Dependent Diffusion-Controlled Reaction of ^·NO and O2^·- at chemical Equilibrium with ONOO^-_.. J.Phys.Chem.B 114:16584-16593, 2010.

37. D. Steinmann, T. Nauser, and W. H. Koppenol. Selenium and Sulfur in Exchange Reactions: A Comparative Study. J.Org.Chem 75:6696-6699, 2010.

36. D. Hofstetter, T. Nauser, and W. H. Koppenol. Hydrogen Exchange Equilibria in Glutathione Radicals: Rate Constants. Chem.Res.Toxicol. 23:1596-1600, 2010.

35. J. M. Gebicki, T. Nauser, A. Domazou, D. Steinmann, P. L. Bounds, and W. H. Koppenol. Reduction of protein radicals by GSH and ascorbate: potential biological significance. Amino Acids 39(5):1131-1137, 2010.

34. M. Sturzbecher-Höhne, R. Kissner, T. Nauser, and W. H. Koppenol. Preparation and Properties of Lithium and Sodium Peroxynitrite. Chem.Res.Toxicol. 21:2257-2259, 2009.

33. B. Galliker, R. Kissner, T. Nauser, and W. H. Koppenol. Intermediates in the Autoxidation of Nitrogen Monoxide. Chem.Eur.J. 15:6161-6168, 2009.

32. R. S. Glass, G. L. Hug, C. Schöneich, G. S. Wilson, L. Kuznetsova, T. Lee, M. Ammam, E. Lorance, T. Nauser, G. S. Nichol, and T. Yamamoto. Neighboring Amide Participation in Thioether Oxidation: Relevance to Biological Oxidation. J.Am.Chem.Soc. 131:13791-13805, 2009.

31. M. Sturzbecher-Höhne, T. Nauser, R. Kissner, and W. H. Koppenol. Photon-Initiated Homolysis of Peroxynitrous Acid. Inorg.Chem. 48:7307-7312, 2009.

30. T. Nauser, G. Casi, W. H. Koppenol, and C. Schöneich. Reversible Intramolecular Hydrogen Transfer between Cysteine Thiyl Radicals and Glycine and Alanine in Model Peptides: Absolute Rate Constants Derived from Pulse Radiolysis and Laser Flash Photolysis. J.Phys.Chem.B 112 (47):15034-15044, 2008.

29. D. Hofstetter, T. Nauser, and W. H. Koppenol. The glutathione thiyl radical does not react with nitrogen monoxide. Biochemical and Biophysical Research Communications 360 (1):146-148, 2008.

28. F. Axthelm, O. Casse, W. H. Koppenol, T. Nauser, W. Meier, and C. G. Palivan. Antioxidant Nanoreactor Based on Superoxide Dismutase Encapsulated in Superoxide-Permeable Vesicles. J.Phys.Chem.B 112 (28):8211-8217, 2008.

27. D. Steinmann, T. Nauser, J. Beld, M. Tanner, D. Günther, P. L. Bounds, and W. H. Koppenol. Kinetics of Tyrosyl Radical Reduction by Selenocysteine. Biochemistry 47:9602-9607, 2008.

26. M. Sturzbecher, R. Kissner, T. Nauser, and W. H. Koppenol. Homolysis of the Peroxynitrite Anion Detected with Permanganate. Inorg.Chem. 46:10655-10658, 2007.

25. T. Nauser, S. Dockheer, R. Kissner, and W. H. Koppenol. Catalysis of Electron Transfer by Selenocysteine. Biochemistry 45:6038-6043, 2006.

24. M. Merkofer, A. Domazou, T. Nauser, and W. H. Koppenol. Dissociation of CP20 from Iron(II)(cp20)₃: A Pulse Radiolysis Study. Eur.J.Inorg.Chem.:671-675, 2006.

23. T. Nauser, W. H. Koppenol, and J. M. Gebicki. The kinetics of oxidation of GSH by protein-bound radicals. Biochem.J. 392 (Pt 3):693-701, 2005.

22. E. Michel, T. Nauser, B. Sutter, P. L. Bounds, and W. H. Koppenol. Kinetics properties of Cu,Zn-superoxide dismutase as a function of metal content. Arch.Biochem.Biophys. 439:234-240, 2005.

21. T. Nauser, G. Casi, W. H. Koppenol, and C. Schöneich. Intramolecular addition of cysteine thiyl radicals to phenylalanine in peptides: formation of cyclohexadienyl type radicals. Chem.Comm.:3400-3402, 2005.

20. T. Nauser, M. Jacoby, W. H. Koppenol, T. C. Squier, and C. Schöneich. Calmodulin methionine residues are targets for one-electron oxidation by hydroxyl radicals: formation of SN three-electron bonded radical complexes. Chem.Comm.:587-589, 2005.

19. T. Nauser, W. H. Koppenol, J. Pelling, and C. Schöneich. UV Photolysis of 3-Nitrotyrosine Generates Highly Oxidizing Species: A Potential Source of Photooxidative Stress. Chem.Res.Toxicol. 17 (9):1227-1235, 2004.

18. T. Nauser, J. Pelling, and C. Schöneich. Thiyl Radical Reaction with Amino Acid Side Chains: Rate Constants for Hydrogen Transfer and Relevance for Posttranslational Protein Modification. Chem.Res.Toxicol. 17:1323-1328, 2004.

17. M. Dubuisson, D. Vander Stricht, A. Clippe, F. Etienne, T. Nauser, R. Kissner, and W. H. Koppenol. Human peroxiredoxin 5 is a peroxynitrite reductase. FEBS Letters 571:161-165, 2004.

16. L. B. Barron, K. C. Waterman, P. Filipak, G. L. Hug, T. Nauser, and C. Schöneich. Mechanism and Kinetics of Photoisomerization of a Cyclic Disulfide, trans-4,5-Dihydroxy-1,2-dithiacyclohexane. J.Phys.Chem.A 108 (12):2247-2255, 2004.

15. R. Kissner, T. Nauser, and C. R Kurz. Peroxynitrous Acid - Where is the Hydroxyl Radical? IUBMB Life 55 (10-11):567-572, 2003.

14. C. R Kurz, R. Kissner, T. Nauser, and W. H. Koppenol. Rapid scavenging of peroxynitrous acid by monohydroascorbate. Free Radical Biol.Med. 35 (12):1529-1537, 2003.

13. T. Nauser and C. Schöneich. Thiyl Radical Reaction with Thymine: Absolute Rate Constant for Hydrogen Abstraction and Comparison to Benzylic C-H Bonds. Chem.Res.Toxicol. 16:1056-1061, 2003.

12. T. Nauser and C. Schöneich. Thiyl Radicals Abstract Hydrogen Atoms from the ^aC-H Bonds in Model Peptides: Absolute Rate Constants and Effect of Amino Acid Structure. J.Am.Chem.Soc. 125:2042-2043, 2003.

11. R. Meli, T. Nauser, P. Latal, and W. H. Koppenol. Reaction of peroxynitrite with carbon dioxide: intermediates and determination of the yield of CO₃^·- and NO₂^·. J.Biol.Inorg.Chem. 7:31-36, 2002.

10. T. Nauser and W. H. Koppenol. The Rate Constant of the Reaction of Superoxide with Nitrogen Monoxide: Approaching the Diffusion Limit. J.Phys.Chem. 106:4084-4086, 2002.

9. A. Daiber, T. Nauser, N. Takaya, T. Kudo, P. Weber, C. Hultschig, H. Shoun, and V. Ullrich. Isotope effects and intermediates in the reduction of NO by P450NOR. J.Inorg.Biochem. 88:343-352, 2002.A. Daiber, T. Nauser, N. Takaya, T. Kudo, P. Weber, C. Hultschig, H. Shoun, and V. Ullrich. Isotope effects and intermediates in the reduction of NO by P450NOR. J.Inorg.Biochem. 88:343-352, 2002.

8. W. A. Prütz, R. Kissner, T. Nauser, and W. H. Koppenol. On the Oxidation of Cytochrome c by Hypohalous Acids. Arch.Biochem.Biophys. 389 (1):110-122, 2001.

7. T. Nauser, M. Merkofer, R. Kissner, and W. H. Koppenol. Gibbs Energy of Formation of Peroxynitrite. Chem.Res.Toxicol. 14:348-350, 2001.

6. S. Herold, M. Exner, and T. Nauser. Kinetic and Mechanistic Studies of the NO-Mediated Oxidation of Oxymioglobin and Oxyhemoglobin. Biochemistry 40:3385-3395, 2001.

5. R. Meli, T. Nauser, and W. H. Koppenol. Direct Observation of Intermediates in the Reaction of Peroxynitrite with Carbon Dioxide. Helv.Chim.Acta 82:722-725, 1999.

4. G. Tabbi, T. Nauser, W. H. Koppenol, and J. Reedijk. A Pulse Radiolysis Study of an Imidazolato-Bridged Asymmetric Dicopper(II) Complex: A Structural and Functional Mimic of Superoxide Dismutase. Eur.J.Inorg.Chem. 1998:1939-1943, 1998.

3. R. Kissner, T. Nauser, P. Bugnon, P. Lye, and W. H. Koppenol. Formation and Properties of Peroxynitrite as Studied by Laser Flash Photolysis, High-Pressure Stopped-Flow Technique, and Pulse Radiolysis. Chem.Res.Toxicol. 11 (5):1285-1292, 1997.

2. T. Nauser and R. E. Bühler. Pivalic Acid as Combined Buffer and Scavenger for Studies of Cloud Water Chemistry with Pulse Radiolysis. J.Chem.Soc.Faraday Trans. 90 (24):3651-3656, 1994.

1. M. von Piechowski, T. Nauser, J. Hoigné, and R. E. Bühler. O₂^·- Decay Catalyzed by Cu²⁺ and Cu⁺ Ions in Aqueous Solutions: A Pulse Radiolysis Study for Atmospheric Chemistry. Ber.Bunsenges.Phys.Chem 97 (6):762-771, 1993.